Wilfred Ndidi will also make a return from injury for the match at the Rudolf Tonn Stadium, a multi-use facility in Rannersdorf
Rohr will shake up the team, after a miserable first half display in Saturday night’s 2-1 loss to England at Wembley.
Expected to miss out on the starting lineup are Ogenyi Onazi and Joel Obi, with Ndidi and John Ogu taking their places.
“Uzoho will start in goal (against Czech Republic).
“Ndidi will start. We followed very well the protocol by Leicester and he is now ready to play,” Rohr told KweséESPN on Tuesday.
Kick-off is 2pm.
Nigeria XI vs Czech Republic: Uzoho Shehu, Ekong, Balogun, Idowu, Ogu, Mikel, Ndidi Moses, Ighalo, Iwobi